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The mesolimbic system, often referred to as the reward system, is a network of brain structures responsible for overseeing the physiological and cognitive aspects of reward processing. Reward, a natural phenomenon, involves the brain associating various stimuli—such as substances, situations, events, or activities—with positive or desirable outcomes. This association prompts adjustments in an individual's behavior, compelling them to seek out that particular positive stimulus. The process of reward involves the synchronized release of various neurotransmitters. Among the brain components involved in reward, dopamine holds a central role. Dopamine is crucial in mediating the perceived reward value associated with activities like consuming food, drinks, engaging social interactions, and substance abuse.